Boston scientists say triglycerides play key role in heart health


The Boston Globe has the article Boston scientists say triglycerides play key role in heart health.

A massive genetic study led by a Boston cardiologist has identified a subset of people who carry rare mutations that cause them to have dramatically lower levels of triglycerides in their blood. Those people, in turn, were 40 percent less likely to have heart disease than people who didn’t have the mutation.
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The findings suggest that scientists should be looking for a way to mimic what the body does in those people with naturally low levels of triglycerides.

I posted my comments to the article on the newspaper’s web site.

Another example of the innumeracy of the press. By now there are hundreds of thousands of statisticians crying out “Correlation does not mean causation.”

It could very well be that the mutation’s side effect of lowering triglycerides may have nothing to do with causing a lower heart disease rate. It might also be that attempting to lower triglycerides by artificial means will have damaging unintended consequences. What countervailing mechanisms will the normal human body bring into play as a consequence of an artificial lowering of triglycerides? It may be that such a lowering without the gene mutation could be fatal.

Is anybody asking these obvious questions? If the doctors involved in this study aren’t aware enough to ask these questions, maybe it is too much to expect the “medical experts” in the news media to think of asking these questions.  Maybe it takes a person like myself with no degree in anything medical to see the forest among the trees.

It may be time for everybody to take another look at RichardH’s post on this blog Diversion–Highway Fatalities and Lemons.

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